Clinicopathological features and treatment strategies of AFP-producing gastric cancer
FANG Yu
ZHANG Yu
WANG Lin
Abstract：Alpha fetoprotein(AFP)-producing gastric cancer is featured with high malignancy, rapid progress, easy to trans-fer, poor prognosis and etc, drawing more attention than ever before. It is considered to be a special type of gastric cancer. Currently, treatment of AFP-positive gastric cancer follows AFP-negative gastric cancer, but the effect is not as good as the common AFP-negative gastric cancer. Therefore, it is very important to explore clinicopathological features of AFP-producing gastric cancer, especially molec-ular biological characteristics on the diagnosis and individualized treatment. This paper summarized the development of the definition of AFP-producing gastric cancer, clinical characteristics, molecular pathology features, treatment status and other aspects.
Keywords：Gastric cancerAlpha fetoprotein(AFP)Individualized treatment
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 569-572 )