Meta analysis of curative effect analysis of spleen preservation in radical gastrectomy for gastric cancer
WANG Dongfeng
ZHANG Dong
XU Fapei
LIU Wei
ZHONG Jian
MA Weihua
SUN Jingfeng
Abstract：Objective To investigate the postoperative complications and 5-year survival rate of splenectomy and spleen pres-ervation in radical gastrectomy for gastric cancer. Methods All eligible case-control studies published up to Febuary 2014 were searched out from PubMed, EMABSE, CBM, CNKI, VIP and WanFang databases. Two reviewers independently identified the litera-ture according to inclusion and exclusion criteria. Meta-analysis was performed using STATA 11?0 software to analyze. Results A total of 16 studies comprising 1949 patients with splenectomy ( resection group) and 2864 patients with splenic preservation ( preservation group) were finally included. The included studies showed good homogeneity in the models of postoperative complications and 5-year survival rate. Overall, the rate of postoperative complications was higher ( OR=1?699,95% CI:1?436-2?009) and the 5-year survival rate was lower ( OR=0?402,95% CI:0?363-0?445) in resection group versus preservation group ( P<0?05) . Conclusion The pres-ervation of spleen in the radical gastrectomy for gastric cancer can reduce the incidence of postoperative complications and improve the survival of patients.
Keywords：Gastric cancerSpleen resectionMeta analysis
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 535-538 )