Analysis of prognostic factors in 92 patients with Siewert Ⅱ and Ⅲ type of cardia cancer
ZHANG Yue?an
LI Xiaoping
LIU Yisheng
ZHU Zhengkui
CHEN Youjun
WU Qichen
CHEN Wu
BAO Fang
Abstract:Objective To explore the prognostic factors in 92 patients with SiewertⅡandⅢtype of cardia cancer. Methods Ninety-two patients with Siewert Ⅱ and Ⅲ type of cardia cancer admitted by our hospital from April 2000 to April 2012 were en-rolled. The clinical data were collected and the patients were followed up for the 5-year survival rate and median overall survival( OS) . The univariate analysis and Cox regression hazard model analysis were used to analyze the factors affecting the prognosis for SiewertⅡandⅢtype of cardia cancer. Results At the end of the follow-up period( September 1, 2012) , 53 out of 92 patients died with the 5-year survival rate of 27?4% and the median OS of 36?0 months. There were significant differences on 5-year survival rates between dif-ferent Siewert type, T stage, N stage and UICC staging(P<0?05). The 5-year survival rates were unrelated to age, histopathology, Lauren type, lymph node dissection and surgical approach. T stage and N stage were independent factors affecting the prognosis for Siewert Ⅱ,Ⅲtype of cardia cancer. Conclusion T stage and N stage were the independent factors affecting the cardia cancer of gas-troesophageal junction. Siewert type can provide useful information for determining the appropriate surgery.
Keywords:Cardia CancerSiewert typePrognostic factor
Publication Date:2014-01-01
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:4( 426-429 )
