Rehabilitation effect of combined therapy using Governor Vessel-regulating acupuncture and repetitive transcranial magnetic stimulation in patients with post-stroke cognitive impairment
SU Qingqing
MIAO Xinqi
Abstract：Objective To investigate the rehabilitation effect of combined therapy applying Governor Vessel-regulating acupuncture and repetitive transcranial magnetic stimulation(rTMS)in patients with post-stroke cognitive impairment(PSCI).Methods A total of 82 patients with PSCI who were admitted from January 2021 to January 2024 were included.They were divided into the control group and the study group using a random number table.The control group(n=41)received rTMS,while the study group(n=41)was supplemented with Governor Vessel-regulating acupuncture on the basis of the control group.Both groups were treated for 4 weeks.The rehabilitation effects and safety of the two groups were compared.The Mini-Mental State Examination(MMSE)and Montreal Cognitive Assessment(MoCA)were used to evaluate the cognitive function of the two groups before and after treatment.The Fugl-Meyer Assessment(FMA)scale and Modified Barthel Index(MBI)were used to evaluate the limb function and activity of daily living(ADL)of the two groups respectively.The levels of serum vascular endothelial growth factor(VEGF)and brain-derived neurotrophic factor(BDNF)before and after treatment were compared between the two groups.Results The total effective rate of rehabilitation in the study group was 95.12%(39/41),which was higher than that of the control group at 80.49%(33/41,P<0.05).After treatment,the scores of the cognitive function assessment scales(MMSE and MoCA),FMA,and MBI in both groups increased compared with those before treatment,which were higher in the study group than in the control group(P<0.05).After treatment,the levels of serum VEGF and BDNF in both groups increased compared with those before treatment,which were higher in the study group than in the control group(P<0.05).There was 1 case(2.44%)of headache and dizziness in the control group,and 1 case(2.44%)of skin redness and swelling in the study group.There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Combined therapy using Governor Vessel-regulating acupuncture and rTMS in patients with PSCI can improve cognitive function,limb function and ADL,improve neurological function of patients,and promote the rehabilitation process,with good safety and reliability.
Keywords：cognitive impairment after strokerepeated transcranial magnetic stimulationGovernor Vessel-regulating acupuncturecognitive functionrehabilitation effectlimb functionbrain-derived neurotrophic factoradverse effect
Publication Date：2026-03-13
Online Publishing Date：2026-03-20(First online date of this platform, not the publication date of the document)
Pages：5( 94-98 )