Analysis of the therapeutic effect of Tongmai Zhitong decoction on patients with angina pectoris after percutaneous coronary intervention for coronary heart disease
LI Bo
ZHANG Liyan
HU Xuejing
ZHANG Xiaoyang
WANG Chunning
YAN Ruyu
Abstract：Objective To study the therapeutic effect of Tongmai Zhitong decoction on patients with angina pectoris after percutaneous coronary intervention(PCI)for coronary heart disease(CHD).Methods Sixty patients with angina pectoris undergoing PCI for CHD admitted from February 2021 to March 2023 were divided into two groups by random number table method,with 30 patients in each group.The control group was given conventional treatment,and on this basis,the observation group was supplemented with Tongmai Zhitong decoction.The course of treatment was 2 months.The efficacy,traditional Chinese medicine(TCM)syndrome scores,Seattle Angina Quantification Scale(SAQ),6-minute walk test(6 MWT),Self-rating Anxiety Scale(SAS),36-Item Short Form Health Survey(SF-36),improvement in New York Heart Association(NYHA)functional class,adverse reactions and major adverse cardiovascular events(MACE)were compared between the two groups.Multivariate logistic regression analysis was used to analyze the related factors influencing the occurrence of MACE.Results The distribution of efficacy and the improvement in NYHA functional class after treatment in the observation group were better than those in the control group(P<0.05).After treatment,the scores of TCM syndromes and SAS in the observation group were lower than those in the control group,while the scores of SAQ,6 MWT and SF-36 were higher than those in the control group(P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05).After 1 year of follow-up,1 patient in the control group was lost to follow-up.The total incidence of MACE in the observation group was 3.33%(1/30),which was lower than 27.59%(8/29)in the control group(P<0.05).The supplementation with Tongmai Zhitong decoction was an independent influencing factor of MACE(OR=0.102;95%CI:0.012,0.887;P=0.039).Conclusion Tongmai Zhitong decoction is helpful to improve the clinical symptoms,negative emotions and cardiopulmonary function in patients with angina pectoris after PCI for CHD,and has certain advantages in reducing the occurrence of MACE.
Keywords：coronary heart diseaseTongmai Zhitong decoctionpercutaneous coronary interventionangina pectorissyndromeanxietycardiopulmonary function
Publication Date：2026-03-13
Online Publishing Date：2026-03-20(First online date of this platform, not the publication date of the document)
Pages：7( 74-80 )