Research progress in the diagnosis and treatment of ulcerative colitis based on the turbid toxin theory
HE Liuting
ZHAO Jing
BAI Haiyan
GENG Nan
ZHANG Tong
LI Bolin
Abstract：Ulcerative colitis(UC)is one of the intractable diseases in the digestive system.Professor Li Diangui,a master of traditional Chinese medicine(TCM),was the first to systematically propose the Turbid Toxin Theory,which provides a new theoretical basis for the TCM syndrome differentiation and treatment of UC.To further clarify the pathogenic mechanism of turbid toxin and guide clinical practice,this study systematically summarizes the clinical experience and mechanism of treating UC based on the Turbid Toxin Theory.Based on this theoretical framework,and focusing on the characteristics of turbid toxin,which is persistent and difficult to eliminate,consuming qi and damaging blood,weidentified the core pathogenesis of UC as turbid toxin obstructing the intestines and disrupting disharmony between qi and blood",and proposed"resolving turbid toxin and harmonizing qi and blood"as the basic therapeutic principles for UC.In clinical practice,the treatment is based on self-formulated prescriptions including the Liqi Huazhuo formula(Qi-Regulating and Turbid-Removing Formula),Quyu Huazhuo formula(the Stasis-Resolving and Turbid-Removing Formula,and Heying Huazhuo formula(the Nutrient-Harmonizing and Turbid-Removing Formula).Medication is refined and modified according to the specific symptoms of patients,so as to better guide clinical practice and improve the therapeutic efficacy.
Keywords：ulcerative colitisdisharmony between qi and bloodTurbid Toxin TheoryTurbid toxin resolving and detoxifyingreview
Publication Date：2026-02-28
Online Publishing Date：2026-03-17(First online date of this platform, not the publication date of the document)
Pages：5( 101-105 )