Clinical Effect and Safety Analysis of Xingnao Kaiqiao Acupuncture Therapy by Academician Shi Xuemin as an Adjunct to Western Medicine for the Treatment of Postpartum Depression
LIU Junjie
WANG Qiangyu
LIU Xia
RONG Shanshan
Abstract：Objective To explore the effect and safety analysis of Xingnao Kaiqiao(refreshing the brain and open-ing the orifices)acupuncture therapy by academician Shi Xuemin as an adjunct to Western medicine in postpartum depression(PPD).Methods A total of 100 patients with PPD admitted from January 2021 to January 2024 were selected and divided into the control group(n=50)and the observation group(n=50)by the random number table method.The control group was treated with Western medicine,while the observation group was treated with Xingnao Kaiqiao acupuncture therapy by acade-mician Shi Xuemin on the basis of the control group.The therapeutic effects,adverse reactions,Hamilton Depression Scale(HAMD),Hamilton Anxiety Scale(HAMA),scores of the Short Form 36 Health Survey(SF-36),and levels of 5-hydroxy-tryptamine(5-HT),estradiol,endorphin,dopamine,progesterone,and luteinizing hormone(LH)were compared between the two groups.Results The total effective rate of the observation group[96.00%(48/50)]was higher than that of the control group[78.00%(39/50)](P<0.05).At 4 and 8 weeks after treatment,the HAMD score and HAMA score of the observation group were lower than those of the control group,while the scores of each dimension of the SF-36 scale were higher than those of the control group(P<0.05).At 4 and 8 weeks after treatment in the observation group,LH,progesterone and enkephalin were lower than those in the control group,while estradiol,5-HT and dopamine were higher than those in the control group(P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion Xingnao Kaiqiao acupuncture therapy by academician Shi Xuemin as an adjunct to Western medicine is effec-tive in the treatment of patients with PPD,and there are no obvious adverse reactions.
Keywords：DepressionPostpartumXingnao KaiqiaoAcupunctureHamilton depression rating scale5-hydroxy-tryptamineEstradiol
Publication Date：2025-06-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 98-103 )