Analysis of Clinical Characteristics of Patients with Persistent Postural-Perceptual Dizziness
ZOU Shuangjun
AN Hongxian
Abstract：Objective To investigate the clinical characteristics of patients with persistent postural-perceptual dizziness(PPPD).Methods The clinical data of 81 patients with PPPD admitted from January 2020 to April 2024 were retrospectively ana-lyzed,and 50 healthy physical examinees during the same period were selected as control group,to analyze the clinical manifesta-tions of PPPD patients.The clinical data,Dizziness Handicap Inventory(DHI),Hospital Anxiety and Depression Scale(HADS),Baker Depression Inventory(BDI)and State-trait Anxiety Inventory(STAI)scores of the two groups were compared,and the risk factors of PPPD were analyzed by multivariate Logistic regression.Results Among 81 patients with PPPD,the main clinical mani-festations were dizziness(n=53,65.43%),unsteadiness(n=36,44.44%)and non-rotational vertigo(n=31,38.27%).A total of 59 patients(72.84%)had identifiable causes,including vestibular neuritis(n=22,37.29%),vestibular migraine(n=15,25.42%),and benign paroxysmal positional vertigo(n=8,13.56%).The scores of DHI,HADS,BDI and STAI in the PPPD group were higher than those in the control group(P＜0.01).Multivariate logistic regression analysis showed that age,female,combined hypertension,combined carotid atherosclerosis and homocysteine(Hcy)were potential risk factors for PPPD.Conclusion Middle-agedfemale population is a group with high incidence of PPPD.Age,gender,combined hypertension,com-bined carotid atherosclerosis and Hcy are all risk factors affecting the occurrence of PPPD.
Keywords：Persistent postural-perceptual dizzinessDizziness Handicap InventoryState-trait Anxiety InventoryAgeHypertensionCarotid atherosclerosisHomocysteineRisk factors
Publication Date：2025-05-13
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 61-65 )