Analysis of Misdiagnosis of Kimura's Disease at the root of the Nose and Literature Review
DING Wenjuan
LIU Longyan
NAN Shuling
DUAN Shihong
GUO Yufen
Abstract：Objective To investigate the clinical characteristics of Kimura's disease(KD)with recurrent nasal mass as the initial symptom and misdiagnosed as hemangioma,to increase the awareness of this disease,so as to improve the initial diagnosis rate and reduce the misdiagnosis rate.Methods The clinical data of a patient with misdiagnosed KD admitted to hospital in January 2024 were retrospectively analyzed,and the relevant literature was reviewed.Results The main clinical manifestations of the patient were recurrent subcutaneous painless mass in the back of the nose.The absolute value and per-centage of eosinophils in the peripheral blood were normal.The patient was diagnosed as hemangioma by B-ultrasound,and was finally diagnosed as KD by pathological examination after two operations for tumors in the nose.From the initial diagnosis of lymphadenosis to the diagnosis after a second recurrence,the misdiagnosis lasted more than 3 years,the prognosis was good,and there was no recurrence at 1-year follow-up.Conclusion KD is rare in clinical practice and prone to misdiagno-sis.Histopathological examination is the gold standard for the diagnosis of KD.Imaging examination,serum IgE level,abso-lute value and percentage of eosinophils in peripheral blood can assist in diagnosis.Surgical resection is an effective means for diagnosis and treatment,and blood routine,urine routine,blood kidney function testing,serum IgE levels,and local ultra-sound examination can serve as monitoring indicators during the follow-up process,providing reference for the formulation of later treatment plan.
Keywords：Nasal massesKimura's diseaseMisdiagnosisNose neoplasmsAngiolymphoid hyperplasia with eosi-nophiliaPathologyEosinophils
Publication Date：2025-05-13
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：7( 14-20 )