Relationship between Red Blood Cell Distribution Width/Albumin Ratio and Microvascular Complications in Type 2 Diabetes Mellitus
HUANG Xuelian
WANG Qin
YANG Chengliang
Abstract：Objective To analyze the relationship between red blood cell distribution width(RDW)/albumin(ALB)ratio(RAR)and microvascular complications in patients with type 2 diabetes mellitus(T2DM).Methods A total of 104 patients with T2DM admitted from June 2022 to March 2024 were selected and divided into the uncombination group(n=60)and the combination group(n=44)according to the presence or absence of microvascular complications.RDW and ALB levels in peripheral blood of all enrolled subjects were detected within 24 h after admission,and RAR was calculated.The basic clinical data,biochemical indexes and RAR of each group were analyzed.Receiver operating characteristic(ROC)curve was used to evaluate the diagnostic value of RAR for microvascular complications in patients with T2DM.Multivariate lo-gistic regression was used to analyze the influencing factors of microvascular complications in patients with T2DM.Results The white blood cell count,serum uric acid,blood urea(Scr),serum cystatin C(CysC),RDW and RAR in the combination group were higher than those in the uncombination group,while ALB was lower than that in the uncombination group(P＜0.05,P＜0.01).Results of ROC curve analysis showed that the area under the curve(AUC)of RAR in peripheral blood in the diagnosis of microvascular complications in T2DM patients was higher than that of RDW and ALB alone.Multivariate logis-tic regression analysis showed that the course of disease,Scr,CysC,ALB and RAR were the influencing factors of microvas-cular complications in patients with T2DM(P＜0.01).Conclusion RAR is abnormally elevated in T2DM patients with mi-crovascular complications,which is an influencing factor of the occurrence of microvascular complications in T2DM patients.In addition,it has a good predictive value for the occurrence of microvascular complications in T2DM patients.
Keywords：Diabetes mellitustype 2Microvascular complicationsRed blood cell distribution width/albumin ratioPredictive valueAnalysis of influencing factor
Publication Date：2025-04-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 58-62 )