Treatment of Perimenopausal Hyperlipidemia Based on ＂Shaoyin as the Pivot＂ Theory

WANG Xueqing; WANG Bin

doi:10.3969/j.issn.1002-3429.2025.07.019

Abstract：Hyperlipidemia is a common disorder of lipid metabolism and abnormal blood lipid levels.Currently,the incidence of hyperlipidemia is increasing year by year.Long-term dyslipidemia can increase the risk of cardiovascular and ce-rebrovascular diseases such as coronary heart disease and stroke,so early management is of great significance.Estrogen pro-duction declines with age in women.Lipid metabolism is affected by estrogen,so the incidence of hyperlipidemia in perimeno-pausal women is higher than that in men of the same age.However,most patients with hyperlipidemia have no obvious clinical symptoms,which makes its harm more hidden.Therefore,screening and prevention of hyperlipidemia in perimenopausal peri-od is particularly important,and it is an important problem to be solved urgently.Western medicine can only temporarily re-duce the level of blood lipid without fundamentally addressing the underlying causes of blood lipid elevation.It is more likely to recur after drug withdrawal with substantial adverse reactions.Traditional Chinese medicine can play an overall regulatory role in preventing the occurrence,development and treatment and improving prognosis of perimenopausal hyperlipidemia,and the long-term effect is significant.In this study,the harm,etiology and pathogenesis,clinical manifestations,treatment of perimenopausal hyperlipidemia and its correlation with Shaoyin pivot mechanism are discussed.Based on the theory of＂Shaoy-in as the pivot＂,it proposes a therapeutic approach by balancing yin-yang through pivot rotation,harmonizing water-fire inter-dependence,and reconciling cold-heat disharmony to restore the Shaoyin pivot function.This approach regulates the character-istics of Shaoyin deficiency in perimenopausal women,thereby influencing the opening-closing functions of taiyin spleen and jueyin liver,and intervening in pathological factors such as phlegm-dampness and blood stasis that cause hyperlipidemia.Ulti-mately,this study provides innovative clinical diagnosis and treatment ideas for perimenopausal hyperlipidemia from the per-spective of TCM pivot theory.