Effect of Clearing Heat and Eliminating Dampness in Type 2 Diabetes Pa-tients with Syndrome of Dampness-heat Blocking Middle Jiao and Its Im-pact on TCM Syndrome Score
LU Lu
AN Ying
CAO Pengyuan
ZHANG Doudou
LIU Yujing
LIU Jinyang
ZHANG Xin
JI Pinchuan
Abstract：Objective To explore the efficacy of clearing heat and eliminating dampness in patients with type 2 dia-betes mellitus(T2DM)with syndrome of dampness-heat blocking middle jiao and its impact on traditional Chinese medicine(TCM)syndrome score.Methods A total of 80 T2DM patients with syndrome of dampness-heat blocking middle jiao admit-ted from January 2020 to December 2023 were selected and divided into research group and control group by random number table method,with 40 patients in each group.The control group was treated with Insulin intensive therapy+Metformin,and the research group was treated with Insulin intensive therapy+Metformin+method of clearing heat and dampness.The clini-cal efficacy,TCM syndrome score,blood glucose,blood lipids,and adverse reactions were analyzed between the two groups.Results The total clinical effective rate of the research group was 97.50%(39/40),which was higher than 80.00%(32/40)of the control group(P＜0.05).After treatment,the TCM syndrome scores,fasting plasma glucose,2 h postprandial plasma glucose,triglyceride,total cholesterol and low-density lipoprotein cholesterol levels in the two groups were lower than those before treatment,which were lower in the research group than in the control group(P＜0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P＞0.05).Conclusion On the basis of convention-al treatment,the combination of clearing heat and dampness is effective in the treatment of type 2 diabetes mellitus with syn-drome of dampness-heat blocking middle jiao,which can significantly reduce the symptoms of patients with high safety.
Keywords：Type 2 diabetes mellitusSyndrome of dampness-heat blocking middle jiaoClearing heat and elimina-ting dampnessTCM syndrome scoreFasting plasma glucoseTriacylglycerolCholesterolAdverse reaction
Publication Date：2025-04-13
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 83-87,97 )