Effect of Platelet-rich Fibrin Combined with Bio-Oss Bone Powder on Peri-odontal Bone Grafting in Patients with Periodontitis and Periodontal Bone Defect
YIN Jun
LI Jing
LI Yue
SONG Wenshang
Abstract：Objective To investigate the application effect of platelet-rich fibrin(PRF)combined with Bio-Oss bone powder in periodontal bone grafting in patients with periodontitis and periodontal bone defects.Methods A total of 120 pa-tients(133 teeth)with periodontitis and periodontal bone defects admitted from June 2022 to June 2023 were selected as the research subjects.All patients received periodontal bone grafting,and were divided into control group(60 patients,65 teeth)and PRF group(60 patients,68 teeth)according to the different materials selected during the operation.The control group used Bio-Oss bone powder during operation,and the PRF group used PRF combined with Bio-Oss bone powder during opera-tion.The therapeutic effect and masticatory efficiency were compared between the two groups.The alveolar bone width,alveo-lar bone height,gingival index,tooth mobility,periodontal probing depth,attachment loss,and tooth aesthetics[pink esthet-ic score(PES)and white esthetic score(WES)]were observed before and at 6 months after operation,and the complications of the two groups were calculated.Results The therapeutic effect and masticatory efficiency of the PRF group were better than those of the control group(P＜0.05).At 6 months after operation,alveolar bone width,alveolar bone height,PES and WES were increased in the two groups,which were higher in the PRF group than in the control group(P＜0.05).At 6 months after surgery,gingival index,tooth looseness,periodontal probing depth and attachment loss in the two groups were lower than those before surgery,which were lower in the PRF group than in the control group(P＜0.05).The total complica-tion rate of the PRF group was lower than that of the control group(P＜0.05).Conclusion PRF combined with Bio-Oss is effective in periodontal bone grafting in patients with periodontitis and periodontal bone defects.It can accelerate periodontal bone regeneration and new attachment formation after surgery,improve the stability and aesthetic effect of the affected teeth,and reduce the total incidence of complications.
Keywords：PeriodontitisPeriodontal bone defectPeriodontal bone graftingPlatelet-rich fibrinBio-Oss bone mealGingival indexTooth mobilityPeriodontal aesthetics
Publication Date：2025-04-13
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 78-82 )