Effect and Safety of CT-guided Synchronous Puncture Biopsy Combined with Radiofrequency Ablation in the Treatment of Pulmonary Nodules
ZHANG Yang
MA Baoke
FAN Min
HUANG Yatao
LI Junpeng
Abstract：Objective To investigate the effect and complications of computed tomography(CT)-guided synchronous puncture biopsy combined with radiofrequency ablation(RFA)in the treatment of pulmonary nodules.Methods In total,80 patients with pulmonary nodules admitted to the hospital from January to October 2023 were divided into the observation group(n=40)and the control group(n=40)according to surgical methods.The control group underwent CT-guided puncture bi-opsy followed by RFA,while the observation group underwent CT-guided synchronous puncture biopsy and RFA.The clinical efficacy,postoperative complications,and pulmonary function were compared between the two groups.Results All 80 pa-tients were diagnosed as malignant pulmonary nodules through pathological examination.There was no significant difference in the total effective rate between the two groups(P＞0.05).The total incidence of pneumothorax,bleeding,pleural effusion and pulmonary infection in the observation group was lower than that in the control group[5.00%(2/40)vs.20.00%(8/40)](P＜0.05).At 3 months after surgery,peak expiratory flow rate and forced vital capacity were lower in both groups than those before operation,which,however,were higher in the observation group than in the control group(P＜0.01).Conclusion CT-guided synchronous puncture biopsy combined with RFA is effective in the treatment of pulmonary nodules,with few complications and relatively less damage to pulmonary function.
Keywords：Pulmonary noduleCT-guidedRadiofrequency ablationNeedle biopsyPneumothoraxPleural effu-sionPeak expiratory flow rateForced vital capacity
Publication Date：2025-03-29
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 38-42 )