Diagnostic Value of Conventional Head Magnetic Resonance Imaging Scan in Acute Cerebral Infarction and Its Value in Predicting Disease Progression
WANG Ting
DONG Jian
GU Xuecun
SHI Guang
HOU Qing
Abstract：Objective To investigate the diagnostic value of conventional head magnetic resonance imaging(MRI)scan in acute cerebral infarction(ACI)and its value in predicting disease progression.Methods A total of 154 patients with suspected ACI were selected from September 2021 to May 2024,and all of them underwent head MRI after admission.Based on the final clinical diagnosis results,the efficacy of conventional head MRI scan in the diagnosis of ACI was analyzed.Ac-cording to the progression of the disease,they were divided into the progression group(n=39)and the non-progression group(n=69).The parameters of conventional head MRI scan[the maximum lesion diameter,number of lesions,severity of white matter osteoporosis,intracranial artery stenosis,brain microhemorrhage,magnetic susceptibility-weighted imaging(SWI)ve-nous asymmetry,clinical and diffusion-weighted imaging(DWI)mismatch]were compared between the two groups,to ana-lyze the effect of conventional head MRI scan parameters on the progression of ACI and its evaluation value.Results The fi-nal clinical diagnosis was 109 patients.Based on the final clinical diagnosis results,the diagnostic sensitivity and specificity of conventional head MRI scan were99.08%(108/109)and97.78%(44/45)respectively.The consistency between conven-tional head MRI scan and final clinical diagnosis results was 98.70%(152/154),and the Kappa value was 0.969(P＜0.001).The maximum lesion diameter in the progression group was greater than that in the non-progression group,the severi-ty of white matter osteoporosis was greater than that in the non-progression group,and the proportion of patients with intracra-nial artery stenosis,cerebral microhemorrhage,SWI venous asymmetry,and clinical mismatch with DWI was higher than that in the non-progression group(P＜0.01).The risk of progression in ACI patients with maximum lesion diameter≥17.40 mm,severity grade of white matter osteoporosis 2+3,intracranial artery stenosis,cerebral microhemorrhage,SWI venous asymmetry,and clinical mismatch with DWI was 2.571,5.091,5.923,2.699,2.850,and 2.875 times of patients with the maximum lesion diameter＜17.40 mm,severity grade of white matter osteoporosis0+1,no intracranial artery steno-sis,no cerebral microhemorrhage,no SWI venous asymmetry,and no clinical and DWI mismatch sign(P＜0.01).The area under the curve(AUC)of the maximum lesion diameter,severity of white matter osteoporosis,intracranial artery stenosis,cerebral microhemorrhage,SWI venous asymmetry and clinical and DWI mismatch for evaluating the progression of ACI was 0.788,0.801,0.785,0.688,0.686 and 0.645,respectively.The AUC of the above parameters in combination for evalua-ting the progression of ACI was the greatest,with sensitivity of 97.44%and specificity of 89.86%.Conclusion Convention-al head MRI scan has high diagnostic value for ACI,and high predictive value for the risk of disease progression.It can pro-vide reference for the development of follow-up intervention plans in clinical practice,so as to improve patient prognosis.
Keywords：Magnetic resonance imagingCerebral infarctionDiagnosisSusceptibility-weighted imagingDiffusion-weighted imagingIntracranial artery stenosisCerebral microhemorrhage
Publication Date：2024-12-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：7( 48-54 )