Clinical Analysis of Brain Glioma Misdiagnosed as Multiple Diseases

KUANG Deli; YAO Guangwei; DAI Hong; YUAN Chunmiao; WANG Xiaoming

doi:10.3969/j.issn.1002-3429.2024.17.004

Abstract：Objective To investigate the causes of clinical misdiagnosis of brain glioma,and to analyze its disease characteristics and preventive measures.Methods The clinical data of 3 patients with brain glioma who were misdiagnosed with other diseases from January 2022 to January 2023 were retrospectively analyzed.Results A female patient was diag-nosed with migraine due to recurrent headache and vomiting.At 2 weeks after conventional analgesic therapy,the symptoms were not relieved.A head magnetic resonance imaging(MRI)examination was performed and revealed space-occupying le-sions in the left temporal lobe,and glioblastoma was confirmed by surgical pathology.A male patient with a history of epilepsy presented with epilepsy and had been taking anti-epileptic drugs for a long time to control the condition.The seizure was more serious and was initially diagnosed as epileptic seizure.Further CT examination of the head showed a mass in the right frontal lobe,which was later confirmed as astrocytoma by operation and pathological examination.A male patient presented with left limb weakness and slurred speech and was initially diagnosed as stroke.After receiving thrombolytic therapy,the symptoms were not significantly relieved.Head CT examination revealed space-occupying lesions in the right parietal lobe,which were later confirmed as anastrocytoma by operation and pathological examination.Misdiagnosis lasted from 6 to 20 d.All patients were given radiotherapy and chemotherapy after operation.The follow-up was favorable and no recurrence or metastasis was ob-served.Conclusion Misdiagnosis of brain glioma is common in clinical practice,which is mainly caused by the non-specific symptoms and imaging features and the lack of clinical experience of the receiving doctors.Improving the cognition of medical staff and improving the diagnostic process can effectively reduce misdiagnosis and improve the diagnostic accuracy,so as to improve the prognosis of patients.