Observation of Therapeutic Effect of Intervention for Obstructive Sleep Apnea Hypopnea Syndrome on Combined Branch Retinal Vein Obstruction
CUI Mingxia
SHU Lingbo
LI Nan
DUAN Ying
ZHANG Yang
LIU Xiaozhe
REN Guoying
Abstract：Objective To investigate the effect of intervention for obstructive sleep apnea hypopnea syndrome(OSAHS)on the efficacy of combined branch retinal vein obstruction(BRVO).Methods A total of 202 patients with BRVO complicated with OSAHS treated from June 2020 to December 2021 were selected and divided into observation group(n=101)and control group(n=101)by random number table method.The control group was given BRVO standard treatment,and the observation group was given BRVO standard treatment and lifestyle intervention(dietary guidance and posture therapy).The mean arterial oxygen saturation(MSaO2)during night time,lowest arterial oxygen saturation(LSaO2),oxygen desaturation index(ODI),best corrected visual acuity(BCVA),macular foveal retinal thickness(CRT),central retinal artery(CRA)end-diastolic blood flow velocity(EDV),peak systolic flow velocity(PSV)between the two groups at the time of enrollment and at 1 month,6 months,1 year and 1.5 years after enrollment,as well as the cumulative incidence of complications and the cumula-tive rate of operation performed in the two groups within 1.5 years after enrollment,were statistically compared.Results The cumulative incidence of complication(13.54%)and cumulative rate of operation(8.33%)in the observation group were lower than those in the control group(26.97%,19.10%)(P<0.05).At 1 month,6 months,1 year and 1.5 years after admission,PSV and EDV of MSaO2,LSaO2 during night time and CRA in observation group were higher than those in control group,while ODI during night time,BCVA and CRT were lower than those in control group(P<0.05,P<0.01).Conclusion Intervention for OSAHS during BRVO treatment can promote the recovery of BRVO combined with OSAHS.
Keywords：Brain retinal vein occlusionObstructive sleep apnea hypopnea syndromeArterial oxygen saturationOxygen desaturation indexVisual acuityMacular foveal retinal thicknessEnd-diastolic blood flow velocityComplication
Publication Date：2024-07-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 89-94 )