Therapeutic Effects of Different Repair Techniques on Patients with Large Tympanic Membrane Perforations and Their Impact on Hearing Threshold and Tympanic Membrane Healing
GUO Weixia
KANG Lili
CHEN Weidong
LIU Nan
WANG Guoguang
JI Hongbin
ZHANG Yanyan
Abstract：Objective To investigate the therapeutic effects of different repair techniques on patients with large tym-panic membrane perforations(TMP)and their impact on hearing threshold and tympanic membrane healing.Methods A to-tal of 120 patients with large TMP from January 2022 to February 2023 were selected and divided into three groups according to a random number table method,with 40 cases in each group.Group A was treated with cribriform cartilage-perichondrium repair,group B with perichondrium-cartilage island repair,and group C with palisade cartilage-perichondrium repair.All three groups were treated with basic fibroblast growth factor gel after surgery.The healing of the tympanic membrane,periop-erative indicators,hearing before and after surgery[500,1000,2000,4000 Hz pure tone audiometry(PTA),average air-bone gap(ABG)],ear stuffiness,and complications were compared among the three groups.Results The healing rate of the tympanic membrane in group A was higher than that in group B and group C,and the intraoperative blood loss was less than that in group B and group C.The duration of operation,healing time of the tragus,length of hospitalization,and postop-erative dry ear time were shorter than those in group B and group C(P＜0.05).The average values of PTA and ABG in group A at 1,3,and 6 months after surgery were lower than those in group B and group C(P＜0.05),and the degree of ear stuffi-ness in group A at 6 months after surgery was lower than that in group B and group C(P＜0.05).The total incidence of com-plications in group A was lower than that in group B and group C(P＜0.05).There was no significant difference in the above indicators between group B and group C(P＞0.05).Conclusion The cribriform cartilage-perichondrium technique used for larger TMP can shorten the duration of operation,reduce intraoperative bleeding,promote tympanic membrane healing,im-prove ear stuffiness and hearing,and reduce the risk of complications.
Keywords：Tympanic membrane perforationCribriform cartilage-perichondrium techniqueTympanic membrane healingHearingEar stuffinessPure tone audiometryAir-bone gapComplications
Publication Date：2024-07-15
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 81-86 )