Effects of Overweight and Obesity on Basilar Artery,Internal Carotid Ar-tery and Vertebral Artery Function in the Population Undergoing Physical Examination
YUE Lin
CHEN Shuchun
WANG Yue
WEI Xueying
DONG Xihong
Abstract：Objective To investigate the correlation between body mass index(BMI)and intracranial artery(basilar artery,internal carotid artery and vertebral artery)function in the population undergoing physical examination.Methods A total of 1169 people undergoing physical examination from June to August 2023 were retrospectively selected.General data,la-boratory indicators,and transcranial Doppler data were collected.According to BMI,they were divided into three groups:nor-mal group(＜24 kg/m2,n=546),overweightgroup(24-＜28 kg/m2,n=484)and obese group(≥28 kg/m2,n=139).The clinical features,laboratory indexes and intracranial arterial flow velocity of the three groups were compared.The correla-tion between BMI and intracranial artery flow velocity was analyzed,and the relationship between BMI and intracranial artery flow velocity was analyzed using multiple linear regression and restricted cubic bars;the critical value of increased risk of slo-wing down intracranial artery flow velocity was determined.Results Compared with normal group,intracranial artery flow ve-locity during diastolic and systolic period and mean blood flow velocity in obese group and overweight group were lower(P＜0.05).The results of multiple linear regression analysis showed that BMI was negatively correlated with intracranial artery flow velocity during diastolic and systolic period and mean blood flow velocity(P＜0.01),but had no correlation with vascular pulsation index and resistance index(P＞0.05).The results of restricted cubic bars showed that there was a linear correlation between basilar artery and bilateral vertebral artery blood flow velocity and BMI(P＞0.05),and a non-linear correlation be-tween bilateral internal carotid artery blood flow velocity and BMI(P＜0.05).Conclusion BMI was negatively correlated with intracranial arterial blood flow velocity in healthy people undergoing physical examination,and when BMI exceeded a spe-cific value(24.18-24.26 kg/m2),the risk of intracranial arterial blood flow velocity was increased.
Keywords：Physical examinationOverweightObesityBody mass indexBasilar arteryVertebral arteryInternal carotid arteryBlood flow velocity
Publication Date：2024-07-15
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：9( 72-80 )