Causes of Misdiagnosis of Lung Fluke Disease as Tuberculous Pleural Effu-sion and Literature Review
KE Na
LI Xin
WANG Xinhong
WANG Jiankun
REN Tao
Abstract：Objective To investigate the causes of misdiagnosis of pleural effusion caused by lung fluke disease and the measures to prevent misdiagnosis.Methods The clinical diagnosis and treatment of 1 patient with lung fluke disease mis-diagnosed as tuberculous pleural effusion were analyzed,and the causes of misdiagnosis were analyzed according to relevant literature.Results The main symptoms of this patient were cough,sputum and fever.Chest CT showed left pleural effusion,and positive TB antibody and erythrocyte sedimentation rate increased significantly.It was misdiagnosed as tuberculous pleural effusion,and the effect of anti-tuberculous therapy was poor.Five months afterwards,the patient was admitted to hospital again due to cough,sputum and fever.Abnormal elevation of eosinophil level was detected in peripheral blood,pleural effu-sion and pleural tissue.The patient had a history of consumption of raw freshwater crab 1 year ago,and the intradermal test for Paragonimus specific antigen(IDTPA)was positive;therefore,the patient was diagnosed as lung fluke disease.The duration of misdiagnosis was 5 months.After diagnosis,the patient was treated with Praziquantel for 4 courses,and the patient achieved clinical cure.Conclusion The elevated eosinophil levels in peripheral blood,pleural effusion and pleural biopsy are of great value in the diagnosis of lung fluke disease.Inquiring about personal history in detail and performing IDTPA in time is the key to early detection and diagnosis of lung fluke disease.
Keywords：Lung fluke diseasePleural effusionMisdiagnosisTuberculosisEosinophilIntradermal tests for Par-agonimus-specific antigenPraziquantelDiagnosis
Publication Date：2024-07-15
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 1-5 )