Study on the Correlation between Vectorcardiogram Parameters and Pul-monary Hypertension in Children and Their Predictive Efficacy for Pulmo-nary Hypertension
PAN Gaoying
PAN Juan
SHUI Quan
WEI Li
Abstract：Objective To investigate the correlation between vectorcardiogram(VCG)parameters and pulmonary hy-pertension(PH)in children and their predictive efficacy.Methods A total of 124 children with suspected PH admitted from February 2020 to February 2024 were selected and divided into the PH group(n=60)and the non-PH group(n=64)ac-cording to the final results of clinical diagnosis.Electrocardiogram(ECG)examination was performed after admission,and routine ECG and VCG were recorded simultaneously.Baseline data,mean pulmonary artery pressure(mPAP)and VCG pa-rameters(QRS maximum vector amplitude,ventricular repolarization gradient azimuth,QRS maximum vector elevation,ven-tricular repolarization gradient elevation,QRS maximum vector azimuth,ventricular repolarization gradient amplitude,QRS-T ratio,and QRS-T angle were higher in PH group than in non-PH group,while between the two groups.The correlation be-tween VCG parameters and mPAP and their impact on PH were analyzed,and the predictive efficiency of VCG parameters on PH was analyzed by receiver operating characteristic(ROC)curve.Results The proportion of children with sinus rhythm in PH group was lower than that in PH group,while the proportion of children with atrial tachycardia,right ventricular hypertro-phy,atrioventricular block block and mPAP were higher than those in PH group(P＜0.01).The ventricular repolarization gradient azimuth,QRS maximum vector elevation,ventricular repolarization gradient elevation,QRS maximum vector azimuth and QRS-T angle in PH group were higher than those in PH group,and the ventricular repolarization gradient amplitude was lower than that in PH group(P＜0.01).Ventricular repolarization gradient azimuth,QRS maximum vector elevation,ven-tricular repolarization gradient elevation,QRS maximum vector azimuth and QRS-T angle were positively correlated with mPAP(r=0.697,0.766,0.836,0.623,0.793,P＜0.001、＜0.001、＜0.001、＜0.001、＜0.001),while ventricular repolar-ization gradient amplitude was negatively correlated with mPAP(r=-0.828,P＜0.001).Logistic regression analysis showed that ventricular repolarization gradient azimuth,QRS maximum vector elevation angle,ventricular repolarization gradi-ent elevation Angle,QRS maximum vector azimuth angle,ventricular repolarization gradient amplitude,QRS-T angle had effects on PH(P＜0.01).ROC analysis showed that the AUC of ventricular repolarization gradient azimuth,QRS maximum vector elevation angle,ventricular repolarization gradient elevation angle,QRS maximum vector azimuth angle,ventricular re-polarization gradient amplitude,and QRS-T angle in combination to predict PH was 0.924,with a sensitivity of 78.33%and a specificity of 92.19%.Conclusion VCG parameters have significant correlation with pulmonary artery pressure,and PH can be predicted and evaluated by VCG parameters in clinical practice,so as to formulate targeted intervention plan and im-prove prognosis.
Keywords：HypertensionpulmonaryChildrenPulmonary artery pressureVentricular repolarization gradient azi-muthQRS maximum vector elevation angleVentricular repolarization gradient elevation angleQRS maximum vector azimuth angleVentricular repolarization gradi
Publication Date：2024-06-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：7( 59-65 )