Value of Enhanced CT Quantitative Parameters in the Diagnosis of Gastro-intestinal Stromal Tumors and Its Relationship with Poor Prognosis
LI Shuchang
GONG Yuanda
LIU Jingkun
Abstract：Objective To investigate the value of enhanced CT quantitative parameters in the diagnosis of gastrointes-tinal stromal tumor(GIST)and its relationship with poor prognosis.Methods In total,120 patients with GIST admitted from March 2020 to March 2022 were selected and divided into non-high risk group(n=68)and high risk group(n=68)accord-ing to postoperative risk grade.Enhanced CT quantitative parameters before surgery were compared between the two groups,and the correlation between enhanced CT quantitative parameters and postoperative risk of GIST was analyzed.The value of enhanced CT quantitative parameters in the diagnosis of postoperative risk of GIST was analyzed by receiver operating charac-teristic(ROC)curve,and preoperative clinical data and enhanced CT quantitative parameters of patients with different prog-nosis at one year after surgery were compared.Multivariate logistic regression analysis was used to analyze the influencing fac-tors of poor prognosis of GIST.Results The onset time and peak time of enhancement in high-risk group were shorter than those in non-high-risk group,while the intensity value of enhancement and half-decline time of intensity were higher or longer than those in non-high-risk group(P＜0.01).The onset time and peak time of enhancement were negatively correlated with the postoperative risk of GIST(r=-0.426,-0.470,P＜0.01),and the value of intensity enhancement and half-decline time were positively correlated with the postoperative risk of GIST(r=0.518,0.635,P＜0.01).The area under the ROC curve(AUC)of the combined diagnosis of GIST patients with high postoperative risk was higher than that of single diagnosis(P＜0.05).Tumor diameter,onset time of enhancement,intensity value of enhancement,peak time and half-decline time of intensi-ty were the factors influencing the prognosis of GIST patients(P＜0.01).Conclusion Quantitative parameters of enhanced CT are closely related to postoperative risk and prognosis of GIST patients.Each quantitative parameter has certain value in the diag-nosis of postoperative risk of GIST patients and has certain guiding significance in the prognosis assessment of patients.
Keywords：Gastrointestinal stromal tumorEnhanced CTOnset time of enhancementPeak timeIntensity value of enhancementHalf-decline time of intensityPostoperative riskPrognosis
Publication Date：2024-06-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 34-39 )