Study of Chain-mediating Pathway,Social Anxiety and Stigma in Mindful-ness and Cognition in Schizophrenia Patients

PENG Qian; LIU Lixin; WANG Longbin; REN Limin; SUN Yan

doi:10.3969/j.issn.1002-3429.2024.06.014

Abstract：Objective To investigate the chain-mediating pathway of social anxiety and stigma in mindfulness and cognition in patients with schizophrenia(SP).Methods A total of 87 SP patients admitted from September 2022 to Septem-ber 2023 were selected and investigated by general data questionnaire,Internalized Stigma of Mental Illness scale(ISMI),so-cial anxiety scale,Mindfulness Attention Awareness Scale and Wechsler Adult Intelligence Scale.Pearson and structural equa-tion model were used to analyze the relationships among social anxiety,stigma,mindfulness and cognition.Results There was no significant difference in intelligence quotient among SP patients with different age,sex,course of disease,level of edu-cation,body mass index and disease type(P＞0.05).Pearson correlation analysis showed that stigma was positively correla-ted with social anxiety(P＜0.01),that mindfulness was negatively correlated with social anxiety and stigma(P＜0.01),that cognition was negatively correlated with social anxiety and stigma(P＜0.01),and that cognition was positively correlated with mindfulness in SP patients(P＜0.01).Structural equation model showed fitting index χ2/df=4.935,RMSEA=0.051,TLI=0.963,CFI=0.977,NFI=0.952.Bootstrap program showed that mindfulness had a direct effect on cognition,and al-so had an indirect positive effect through the parallel mediating effect of social anxiety and stigma or the chain-mediating effect of social anxiety and stigma.Conclusion In the clinical rehabilitation of SP patients,we should pay attention to the effects of mindfulness intervention in different action pathways,and take appropriate approaches to improve the cognitive function of pa-tients according to the pathway.