Correlation of 12-zone Lung Ultrasound Score with Severity of Neonatal Respiratory Distress Syndrome and Its Diagnostic Value
MA Hongxin
LIU Lijing
DU Rui
DI Xiaoling
GU Hua
Abstract：Objective To explore the correlation between the 12-zone lung ultrasound score and the severity of neo-natal respiratory distress syndrome(NRDS)and its application value in diagnosis.Methods Eighty children with NRDS treated from March 2020 to July 2022 were included in the NRDS group,and 80 newborns with non-pulmonary diseases during the same period were included in the control group.All newborns were examined by chest X-ray,12-zone lung ultrasound score and oxygenation index.The ultrasound signs,blood gas oxygenation index and 12-zone lung ultrasound scores of the two groups were analyzed,and the correlation between 12-zone lung ultrasound scores and the severity of NRDS was analyzed.The efficacy of 12-zone lung ultrasound scores in diagnosing children with different severity of NRDS was analyzed.Results In NRDS group,the detection rates of bronchial air sign,B line fusion,A line disappearance,lung consolidation,diffuse pulmo-nary edema and pleural line abnormality were higher than those in control group(P＜0.01).The oxygenation index of NRDS group was lower than that of control group,and the 12-zone lung ultrasound score was higher than that of control group(P＜0.01).The 12-zone lung ultrasound scores of severe children were higher than those of moderate and mild children,and high-er in moderate children than in mild children(P＜0.05).There was a significant positive correlation between chest X-ray grading and 12-zone lung ultrasound scores(r=0.782,P＜0.05).The oxygenation index of severe children was lower than that of moderate and mild children,and lower in moderate children than in mild children(P＜0.05).There was a significant negative correlation between the oxygenation index and the 12-zone lung ultrasound scores(r=-0.861,P＜0.05).The area under the ROC curve(AUC)of 12-zone lung ultrasound scores in the diagnosis of mild,moderate and severe NRDS children were 0.875,0.894 and 0.922,respectively.Conclusion The 12-zone lung ultrasound score can comprehensively and sys-tematically evaluate and accurately reflect the condition of children with NRDS,and the real-time monitoring of the condition of children based on the score level in clinical practice can provide important information and basis for clinical treatment of the disease.
Keywords：Respiratory distress syndromeNewborns12-zone lung ultrasound scoreOxygenation indexChest X-rayCorrelationDiagnostic valueReceiver operating characteristic curve
Publication Date：2024-05-15
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 48-52 )