Effect of Modified Prone Position Ventilation on Respiratory Circulation,Rehabilitation Indicators,and Complications in Conscious Patients with Vi-ral Pneumonia
YAO Na
LIU Juanjuan
ZHANG Tingting
Abstract：Objective To investigate the effects of modified prone position ventilation(PPV)on respiratory circula-tion,rehabilitation indicators,and complications in conscious patients with viral pneumonia(VP).Methods In total,134 VP patients treated from August 2021 to June 2023 were selected and divided into research group(n=67)and control group(n=67)according to the random number table method.The control group received conventional PPV,while the research group re-ceived modified PPV.The rehabilitation indicators,blood gas indicators[oxygenation index ratio of arterial partial pressure(PaO2)of oxygen to fractional inspired oxygen(PaO2/FiO2),arterial partial pressure of carbon dioxide(PaCO2),blood oxy-gen saturation(SpO2)],hemodynamic indicators[heart rate(HR),central venous pressure(CVP),mean arterial pressure(MAP)],respiratory function indicators[plateau pressure(Pplat),airway peak pressure(Ppeak),mean airway pressure(Pmean)],inflammatory indicators[interleukin-6(IL-6),granulocyte-macrophage colony stimulating factor(GM-CSF),tumor necrosis factor-α(TNF-α)],complications,and incidence of pressure injury were compared between the two groups.Results The length of hospitalization was shorter in the research group than in the control group(P＜0.05).The PaCO2,PaO2,PaO2/FiO2,SpO2 at 2,4,8,12,and 16 h in prone position,as well as Ppeak,Pmean,Pplat,GM-CSF,IL-6,and TNF-α at 24 and 36 h in prone position,were significantly improved compared with those before prone position in both groups(P＜0.05),which,however,showed no significant difference(P＞0.05).There was no significant intergroup and intra-group difference in CVP,MAP,and HR at different time points(P＞0.05).The total incidence of complications was lower in research group than in control group[2.99%(2/67)vs.(11.94%(8/67))],and the incidence of pressure injury was lower than that of control group[2.99%(2/67)vs.(13.43%(9/67)](P＜0.05).Conclusion In conscious patients with VP,modified PPV can achieve similar auxiliary therapeutic effects as conventional PPV,improve oxygenation and respir-atory circulation functions,reduce the risk of complications and pressure injury,and accelerate the recovery of the disease.
Keywords：PneumoniaviralModified prone position ventilationBlood gas analysisHemodynamicsInterleukin-6Tumor necrosis factor-αMean airway pressureComplications
Publication Date：2024-05-15
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 24-29 )