Observation on the Application Effect of Modified Prone Position Ventila-tion in Conscious Patients with Viral Pneumonia
ZHANG Tingting
YAO Na
LIU Juanjuan
Abstract：Objective To observe the application effect of modified prone position ventilation(PPV)on conscious patients with viral pneumonia.Methods A total of 80 patients with viral pneumonia who were conscious from April 2022 to February 2023 were selected and randomly divided into two groups,with 40 cases in each group.The control group received conventional PPV,while the observation group received modified PPV.The recovery conditions,as well as the changes in blood gas indicators[arterial partial pressure of oxygen(PaO2),partial pressure of carbon dioxide(PaCO2),oxygen satura-tion(SaO2),oxygenation index]before and after prone position,hemodynamic indicators[heart rate(HR),mean arterial pressure(MAP),stroke volume variation(SVV),stroke volume index(SVI)],respiratory function indicators[mean airway pressure(Pmean),peak airway pressure(Ppeak),lung dynamic compliance(Cydn)],serum nuclear transcription factor-κB(NF-κB)changes,and pressure injury conditions of the two groups were observed.Results The length of hospitalization in the observation group was shorter than that in the control group(P＜0.01).At 1,2,4,8,and 16 h after prone position,the PaO2,PaCO2,SaO2,and oxygenation index in both groups improved compared with those before prone position.At 24 and 36 h after prone position,the Pmean,Ppeak,and Cydn in both groups improved compared with those before prone posi-tion.At 24 and 36 h after prone position,the serum NF-κB level improved compared with that before prone position(P＜0.05),but there was no difference between the two groups(P＞0.05).There was no difference in HR,MAP,SVV,and SVI between the two groups and in the same group at different time points(P＞0.05).The incidence of pressure injury in the observation group was 2.50%(1/40),which was lower than that in the control group(20.00%,8/40)(P＜0.05).Con-clusion Modified PPV in conscious patients with viral pneumonia produces similar auxiliary therapeutic effects as convention-al PPV,which can improve oxygenation,respiratory function and lung compliance,reduce inflammatory response and pressure injury events,and promote early recovery of the disease.
Keywords：Viral pneumoniaModified prone position ventilationConsciousnessPressure injuryArterial partial pressure of oxygenBlood oxygen saturationMean arterial pressurePeak airway pressure
Publication Date：2024-04-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：7( 35-41 )