Imaging Characteristics and Clinical Prognostic Value of Enhanced MRI Scanning in Patients with Meningioma

ZHANG Hui; CUI Yanqiu; LIU Yan

doi:10.3969/j.issn.1002-3429.2024.04.014

Abstract：Objective To explore the imaging characteristics of enhanced MRI scanning in patients with meningioma and to analyze its clinical prognostic value.Methods A total of 87 patients with meningiomas admitted from October 2019 to October 2022 were selected,all of whom received enhanced MRI scanning before surgery,followed by tumor resection and/or skull base repair.The prognosis was evaluated at 6 months after surgery according to Glasgow Outcome Scale(GOS),and they were divided into poor prognosis group(GOS grade Ⅱ-Ⅲ)and good prognosis group(GOS grade Ⅳ-Ⅴ).The imaging characteristics of MRI enhanced scanning of patients with different pathological grades were compared,and the correlation be-tween imaging characteristics and pathological grades was analyzed.The imaging characteristics of enhanced MRI scanning in patients with different prognosis were compared,and the influencing factors of poor prognosis in patients with meningioma were investigated.The value of enhanced MRI imaging characteristics in predicting the prognosis of patients at 6 months after sur-gery was analyzed.Results There were significant differences in peritumoral edema,blood vessel flow void signal,maximum contrast enhancement rate(MCER),tumor maximum diameter,tumor volume(V),tumor surface area density(Sv),vol-ume transfer constant(Ktrans)and extracellular volume fraction(Ve)among patients with meningioma of different WHO pathological grades(P<0.05).Peritumoral edema,blood vessel flow void signal,MCER,tumor maximum diameter,V,Sv,Ktrans,and Ve were positively correlated with pathological grade in meningioma patients(P<0.05).The proportion of peritumoral edema and blood vessel flow void signal in the good prognosis group was lower than that in the poor prognosis group,and MCER,tumor maximum diameter,V,Sv,Ktrans and Ve levels were lower than those in the poor prognosis group(P<0.01).Peritumoral edema,blood vessel flow void signal,MCER,tumor maximum diameter,V,Ktrans and Ve were independent influencing factors for poor prognosis in patients with meningioma(P<0.05).The combined prediction of per-itormal edema,blood vessel flow void signal,MCER,maximum tumor diameter,V,Ktrans and Ve had the largest area under the receiver operating characteristic curve,which was greater than that predicted by each indicator alone(P<0.05).Con-clusion Enhanced MRI imaging characteristics of meningioma patients are closely related to their pathological grade,and the combination of peritumoral edema,blood vessel flow void signal,MCER,tumor maximum diameter,V,Ktrans and Ve have higher predictive value for the prognosis of meningioma patients.