Research Progress on the Th1/Th2 Cytokines in the Pathogenesis of Respir-atory Distress Syndrome in Premature Infants
YANG Xiaolan
XIE Meiling
LIAO Xiaolan
LIU Li
LIU Yanru
Abstract：Respiratory distress syndrome(RDS)often strike premature infants,and its pathogenesis is mainly related to Th1/Th2 cytokine imbalance,especially the predominant Th1 cytokine.However,the specific mechanism of Th1/Th2 cyto-kine imbalance participating in the occurrence and development of RDS has not yet been well understood.Clarifying the patho-genesis of RDS and taking reasonable and effective treatment measures is the key to reducing the mortality of premature chil-dren with RDS.Therefore,by referring to relevant research data at home and abroad,this study focused on the expression of Th1/Th2 cytokines in premature children with RDS and its mechanism of action,in order to provide new ideas for the treat-ment of this disease.
Keywords：Respiratory distress syndromeInfantprematureTh1 cytokinesTumor necrosis factor-αTh2 cyto-kinesInterleukin-4Pulmonary surfactantReview
Publication Date：2023-12-22
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 146-149,154 )