Effects of Total Intravenous Anesthesia on ONSD,Hemodynamics and Ne-onates in Puerperas with Severe Preeclampsia

ZHAN Xiajuan; XIAO Yongtao; WEN Qiaoxing; DONG Shuhua

doi:10.3969/j.issn.1002-3429.2023.08.024

Abstract：Objective To analyze the effects of total intravenous anesthesia(TIVA)on optic nerve sheath diameter(ONSD),hemodynamics and neonates in puerperas with severe preeclampsia.Methods A total of 108 pregnant women with severe preeclampsia treated from November 2019 to July 2022 were selected and divided into observation group(n =56)and control group(n =52)according to different anesthesia methods.The observation group was given TIVA,and the control group was given epidural anesthesia.Operation-related indicators,ONSD,hemodynamics[systolic blood pressure(SBP),di-astolic blood pressure(DBP),mean arterial pressure(MAP),heart rate],neonatal Apgar score and neonatal intubation rate were compared between the two groups.Results The time of anesthesia induction and fetal delivery in the observation group was shorter than that in the control group(P＜0.01).In observation group,ONSD at 5 min after anesthesia,at 5 min after delivery and at 30 min after operation were lower than those before anesthesia and those in control group(P＜0.05).DBP was higher at 30 min after operation in observation group than in control group,and HR at 5 min after anesthesia,at 5 min af-ter delivery and at 30 min after operation was faster than those in control group(P＜0.05).The 5 min Apgar score of the ob-servation group was higher than that of the control group(P＜0.01).There was no significant difference in the intubation rate of neonates between the observation group and the control group[(8.92%,5/56)vs.(11.53%,6/52)](P＞0.05).Conclusion Compared with epidural anesthesia,TIVA can improve ONSD of puerperas with severe preeclampsia,signifi-cantly reduce intracranial pressure,and have fewer effects on hemodynamics and neonates.