Analysis of CT Findings and Misdiagnosis of Primary Extra-nodal Diffuse Large B-cell Lymphoma
TAN Yuanman
ZHU Gangming
YANG Gai
DONG Yongde
ZHU Ruiting
XU Tuanxin
Abstract：Objective To explore CT findings in detecting primary extra-nodal diffuse large B-cell lymphoma(DLBCL),and to summarize causes of CT misdiagnosis and provide preventive measures.Methods The clinical and CT im-aging data of 8 patients with extranodal DLBCL diagnosed by operation or biopsy from January 2019 to December 2021 were retrospectively analyzed.Results Of 8 patients,there were 2 cases of sore throat with foreign body sensation and dull pain in upper abdomen respectively,and 1 case of lower back pain,neck swelling and pain,right nose occlusion with hearing loss in right ear,and low fever and edema in both lower limbs,respectively.Six patients were initially misdiagnosed by CT as naso-pharyngeal carcinoma(n =1),tonsil neurogenic tumor(n =1),Hashimoto thyroiditis(n =1),splenic metastasis(n =1),colon cancer(n =1)and pancreatic cancer(n =1).Another 2 patients were confirmed by CT at initial diagnosis.Misdiagno-sis lasted from 1 to 7 d.All patients were pathologically confirmed to have DLBCL,and were given corresponding treatment,with good prognosis.Conclusion Primary extra-nodal DLBCL lacks specificity in clinical manifestations,and CT imaging manifestations have certain common features that have important diagnostic and differential diagnostic values for this disease,and confirmation of the diagnosis relies on pathological examination.
Keywords：Lymphomalarge B-celldiffuseMisdiagnosisNasopharyngeal neoplasmsTonsillar neoplasmsCo-lonic neoplasmsPancreatic neoplasmsTomographyspiral computedPrognosis
Publication Date：2023-08-22
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 31-34 )