Clinical Analysis of Plasma Cell Mastitis Misdiagnosed as Breast Cancer and Intraductal Papilloma before Operation

CAO Xinhe; YANG Lu

doi:10.3969/j.issn.1002-3429.2023.07.001

Abstract：Objective To investigate the causes and preventive measures of plasma cell mastitis misdiagnosed as breast cancer and intraductal papilloma before operation.Methods The clinical data of 14 patients with plasma cell mastitis who were misdiagnosed as breast cancer and intraductal papilloma before surgery and admitted to our hospital from January 2019 to June 2021 were retrospectively analyzed.Results All of the 14 cases were non-lactating females,and the main symptoms were unilateral mammary mass and local mammary pain.There were 9 cases with nipple discharge,7 cases with lo-cal skin redness and swelling and skin temperature rise,5 cases with nipple depression,5 cases with local mammary tender-ness,and 8 cases with enlargement of palpable ipsilateral axillary lymph nodes.The initial diagnosis was breast cancer in 8 cases and intraductal papilloma in 6 cases.Elective resection of breast lesions was performed.Rapid frozen pathologic exami-nation during operation revealed plasma cell mastitis.The misdiagnosis lasted 5-7 d.Then,10 cases underwent breast seg-mentectomy and 4 cases underwent breast duct resection.All patients were discharged from the hospital after healing by first intention.No recurrence was observed after 2 years of follow-up.Conclusion The clinical incidence of plasma cell mastitis is low,the early manifestations are often atypical,and it is more likely to cause misdiagnosis before pathological examination.Strengthening the clinician's understanding of this disease,enhancing the vigilance,and performing fine needle puncture biop-sy as soon as necessary are needed to improve the preoperative diagnosis rate of this disease.