Analysis of Risk Factors for Carotid Atherosclerosis in Patients at High Risk of Stroke

REN Hui-cai; WANG ZHi-xian; FENG Nan; DONG Jun-chan; ZHANG Yan-min; WANG Li

doi:10.3969/j.issn.1002-3429.2018.06.031

Abstract：Objective To explore the risk factors for carotid atherosclerosis (CAS) in the population at high risk for stroke. Methods A total of 1200 patients at high risk of stroke screened from a community in Shijiazhuang, Hebei Province from February 2015 to February 2017 were selected as study subjects. According to the results of neck ultrasound examination, all the patients were divided into carotid intima-media thickness ( CIMT) group , non-CIMT group, plaque formation group and non-plaque formation group, The distribution of risk factors for CAS in all groups was documented. Results Univariate logistic regression analysis showed that sex, age, education, past med-ical history, physical exercise, and history of drinking were significantly different between CIMT group and non-CIMT group as well as between plaque formation group and non-plaque formation group. CIMT and plaque formation were positively correlated with age, history of stroke, hypertension, smoking, diabetes, coronary heart disease and physi-cal exercise (P<0.05), and negatively correlated with education, family history of stroke and regular consumption of fruits (P<0.05). Multivariate Logistic regression analysis showed that smoking, age, history of stroke, diabetes and physical exercise were risk factors for CAS in patients at high risk of stroke. Conclusion Adequate physical ex-ercise, good living style and active control of risk factors are beneficial in the prevention of CAS in people at high risk of stroke.