Misdiagnosis Analysis of Systemic Lupus Erythematosus Characterized by Polyserous Effusions and Elevated IgE in the Elderly
LIN Lan
CHEN Li-min
LIN Ting-yan
TAN Xue-xue
Abstract：Objective To analyze clinical features and the causes of misdiagnosis and preventive measures of systemic lupus erythematosus ( SLE) in the elderly. Methods The clinical data of an elderly SLE patient with polyserous effusions and significantly elevated immunoglobulin E ( IgE) in our hospital was retrospectively analyzed. Results This patient was admitted to our hospital for three times with cough and shortness of breath. The main man-ifestations included pleural effusion, pericardial effusion, elevated IgE and multiple enlarged lymph nodes, which were misdiagnosed as pneumonia. Anti-infection and antiasthetic treatment were not effective. Whatˊs worse, multi-systematic damage occurred subsequently, such as pleural and pericardial effusion, significantly increased IgE level, declined hemoglobin, platelet and complement C3, C4, as well as increased globulin. After consultation of rheuma-tologist, she was diagnosed as SLE and given anti-inflammatory and immunosuppressive treatment, and subsequently, the condition was improved. After three months of follow-up, the patient was in good condition. Conclusion In the elderly patients with unexplained polyserous effusions and elevated IgE, SLE should be considered. Relevant tests should be performed as early as possible in order to avoid or reduce misdiagnosis and mistreatment.
Keywords：Lupus erythematosussystemicImmunoglobulin EAgedMisdiagnosisPneumonia
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 31-33 )