lism in Elderly Patients with Uremia
DONG Yan-hua
WANG Lin-lin
ZHU Gui-dong
Abstract：Objective To investigate the effects of different types of flux in hemodialysis on parathyroid hor-mone (PTH),calcium(Ca) and phosphorus(P) metabolism in elderly patients with uremia. Methods A total of 88 elderly patients with uremia admitted to our hospital from 2016 January to 2017 January were divided into low-flux hemodialysis group(LFHD) group and high-flux hemodialysis group(HFHD) group, with 44 cases in each group, according to different types of fluxes in hemodialysis. PTH,Ca,P,serum creatinine (SCr),β2-MG, interleukin-6 (IL-6) and C reactive protein(CRP) level were compared in two groups before treatment and at 6 months after treat-ment. Results After treatment,the levels of P and PTH were significantly lower in HFHD group than those before treatment (P<0.05),and the difference was statistically significant(P<0.05). Six months after treatment, the levels of SCr,β2-MG,IL-6 and CRP in the two groups were decreased compared with those before treatment (P<0.05 or P<0.01),and the levels of those indicators were lower in HFHD group than in LFHD group(P<0.05). Conclusion HFHD can improve the level of PTH and metabolism of Ca and P in elderly patients with uremia,amel-iorate inflammatory response,protect renal function and reduce renal injury.
Keywords：UremiaAgedRenal dialysisParathyroid hormoneCalciumPhosphorus
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 94-98 )