Analysis of Causes and Treatment Effect of Adult Patients with Chronic Cough

HAN Bing-chao; LIU Xiao-hu; REN Mao; LIU Xiao-jing; WANG Tian-yi

doi:10.3969/j.issn.1002-3429.2018.02.013

Abstract：Objective To analyze causes and treatment effect of adult patients with chronic cough. Methods A to-tal of 109 adult outpatients with chronic chough during October 2015 and September 2016,who had met the inclusion criteria, were recruited in the study. On the basis of Guideline on Diagnosis and Treatment of Cough(2009 edition),the patients were diagnosed and treated,and then the causes and treatment effects were analyzed. Results Among the 109 outpatients,96 pa-tients were confirmed the diagnosis of chronic chough, in which 89 patients had a single cause,6 patients had two kinds of causes and 1 had three kinds of causes;other 13 patients with chronic chough showed etiology unknown. The top three causes of chronic cough in the 96 confirmed patients were cough variant asthma(CVA),upper airway cough syndrome(UACS) and atopic cough (AC). Incidence rate of CVA in female patients with chronic chough was significantly higher than that in male patients with chronic chough (P<0.05). The age of 6 cough patients induced by angiotensin converting enzyme inhibitor was more than 50 years old. After treatment,78 patients(71.6%) were cured,29 patients(26.6%) were effective,and 2 pa-tients were noneffective in the 109 patients,and the total effective rate was 98.2%. Conclusion CVA, UACS and AC are the most common reasons of chronic cough. CVA is more frequently found in females that that in males,and most treatments for chronic cough are effective.