Predictive Value of Serum High-sensitivity C-reactive Protein and Prealbumin Ratio in Patients with Acute Myocardi-al Infarction Complicated with Heart Failure

LING Jie-bing; MA Bin

doi:10.3969/j.issn.1002-3429.2018.01.029

Abstract：Objective To analyze the predictive value of serum high-sensitivity C-reactive protein and prealbumin ra-tio in patients with acute myocardial infarction (AMI) complicated with heart failure(HF). Methods The clinical data of 120 patients with acute myocardial infarction were retrospectively analyzed admitted to our hospital from February 2014 to Oc-tober 2016, according to the Killip cardiac function classificationⅡor higher level as a basis for the concurrent HF, 120 pa-tients were divided into HF group and control group, 70 cases of control group and 50 cases of HF group. We compare the data of the two groups and analyze the related factors of AMI and HF. To observe the levels of hs-CRP and PAB in HF group, and analyze the correlation between them. Results Age, NT-proBNP, serum hs-CRP, PAB were the factors affecting AMI. The HF group gradually increased the level of hs-CRP with the function of Killip, and the PAB level gradually decreased, and the comparison with non-hr group was statistically significant (P <0. 01). HF group hs-CRP level and Killip cardiac function grading were positively correlated (r=0. 567, P=0. 012), PAB level and Killip cardiac function grading were negatively cor-related (r= -0. 466, P=0. 025 ). The sensitivity of hs-CRP/PAB in the diagnosis of AMI was 96. 98％, the specificity was 95. 68％, the area under the ROC curve was 0. 98, and the difference of diagnostic value of other factors was statistically sig-nificant (P<0. 05). Conclusion The hs-CRP and PAB levels were raised when AMI was concurrent with HF, and hs-CRP/PAB was closely related to AMI combined with HF. The higher the ratio of HF, the greater the risk of HF, which could be used as the predictor of AMI's concurrent HF.