Effect of Pharmacists Intervention on Rational Use of Tanreqing Injections

LI Chang; CHANG Bing; WANG Guang-wei; YANG Long-fei; ZHENG Xiao; ZHAO Tie-mei

doi:10.3969/j.issn.1002-3429.2017.12.036

Abstract：Objective To investigate effect of pharmacists intervention on rational use of Tanreqing injections. Meth-ods A total of 428 inpatients using Tanreqing injections during January 2015 and January 2016 were divided into interven-tional group (n=214) and control group (n=214) according to random number table method. All inpatients received treat-ments such as Tanreqing injections, relieving cough, expelling phlegm, spasmolysis and antiasthma, clearing away the heat e-vil and expelling superficial evils, and pharmacists interfered during using Tanreqing injections in intervention group. Unrea-sonable usage conditions of Tanreqing injections, incidence rate of adverse drug reactions ( ADR) , total hospitalization expen-ses, hospitalization days and proportion of total cost for Tanreqing injections to total hospitalization expenses were analyzed in two groups. Results There were significantly differences in compatibility of drugs with Potassium Chloride and so on, no use of regular solvent dosage, over indications of drug usage and incidence rate of overdosage use in two groups (P<0. 05). ADR incidence rates were 1. 87% in interventional group and 9. 81% in control group, and the difference was statistically signifi-cant between the two groups (P<0. 05). Compared with those in control group, values of total hospitalization expenses, hos-pitalization days and proportion of total cost for Tanreqing injections to total hospitalization expenses were significantly de-creased in interventional group (P<0. 05). Conclusion Pharmacists intervention in rational use of Tanreqing injections may decrease ADR incidence rate, hospitalization days and hospitalization expenses and ensure rational use of drugs.