Correlation between Blood Pressure Parameters and Serum NT-proBNP levels in Hypertension Patients during Fol-low-up Period
AN Shao-bo
XU Lei
DU Xiao-jing
HU Xi-tian
WANG Yun-ying
WU Zhi-hong
Abstract：Objective To investigate the correlation between blood pressure parameters and serum N-terminal pro-B-type natriuretic peptide ( NT-proBNP) in hypertension patients during follow-up period. Methods A total of 44 patients with essential hypertension during November 2016 and May 2017 received regular follow-up and blood pressure test every month for continuous 12 months. The values of standard deviation of systolic blood pressure in 12 months (12MSSD), variation coeffi-cient of systolic blood pressure in 12 months (12MSCV), the mean systolic blood pressure in 12 months (12MMS) and the mean diastolic blood pressure in 12months (12MMD) were calculated, and parameters such as plasma triglyceride, total cho-lesterol, high density lipoprotein cholesferol, glycosylated hemoglobin and serum creatinine were recorded, and correlations between the parameters with serum NT-proBNP were analyzed. Results In this study, 12MMS was (130 ± 13) mmHg, and 12MMD was (69 ± 6) mmHg, and the mean NT-proBNP value was (232. 0 ± 25. 7) pg/ml, meanwhile changes of blood pressure were seasonal. Serum NT-proBNP showed no correlations with above indexes of laboratory examinations, but it was obviously correlated with 12MMS, and 12MMS was independent factor of serum NT-proBNP (β=0. 613, P<0. 001). Con-clusion Serum NT-proBNP is closely correlated with 12MMS in hypertension patients, and it can be used as a monitoring in-dex for blood pressure treatment.
Keywords：HypertensionN-terminal pro-B-type natriuretic peptideSystolic pressureDiastolic pressure
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 76-79 )