Thrombelastogram in Guidance of Clinical Treatment during Perioperative Period of Cardiac Surgical Procedures: a Meta Analysis
HU Gui-feng
ZHANG Bin
LI Jun-jie
YIN Wen
Abstract：Objective To discuss effectiveness and safety of thrombelastogram (TEG) in guidance of clinical treatment during perioperative period of cardiac surgical procedures.Methods Randomized controlled trails (RCT) pertinent papers about TEG in guidance of clinical treatment during perioperative period of cardiac surgical procedures were searched on CBM (1990-2016), CNKI (1990-2016), PubMed (1975-2016), The Cochrane Library (1980-2016) and Embase (1975-2016) databases by computer.The papers were evaluated by improved Jadad scale, and corresponding papers were selected and performed data analysis by Review Manager 5.3 statistics software.Results A total of 10 papers were included in this study, and there were 6 high-quality papers and 4 poor-quality papers.Meta analysis showed that there were significant differences in erythrocyte transfusion rate [RR=0.83, 95％CI (0.75, 0.92), P=0.0004], fresh frozen plasma of transfusion rate [RR=0.41, 95％CI (0.32, 0.52), P<0.00001] and postoperative reoperation rate [RR=0.56, 95％CI (0.33, 0.97), P=0.04] during perioperative period in TEG group compared with those in control group.Conclusion TEG can effectively guide clinical treatment during perioperative period of cardiac surgical procedures with good safety.
Keywords：ThrombelastogramCardiac surgical proceduresPerioperative periodMeta analysis
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 65-69 )