Predictive Value of Biological Markers for Postoperative Atrial Fibrillation in Patients with Off-pump Coronary Artery Bypass Grafting
ZHANG Ming-xin
WANG Hui-shan
ZHU Yan
HAN Hong-guang
Abstract：Objective To investigate predictive values of preoperative N-terminal pro-brain natriuretic peptide (NT-proBNP), high-sensitivity troponin T (hs-cTNT) and red blood cell distribution width (RDW) for postoperative atrial fibrillation (AF) in patients with off-pump coronary artery bypass grafting (OPCABG).Methods A total of 240 patients undergoing selective OPCAB only were divided into AF group (n=66) and sinus rhythm (SR) group (n=174) according to whether or not having postoperative AF.Preoperative basic data, results of laboratory test and changes of perioperative parameters were recorded, and independent predictors in prediction of postoperative AF after OPCAB were analyzed in two groups.Results There were significant differences in age, preoperative acute myocardial infarction, taking statins preoperatively and left atrium diameter between two groups (P<0.05).Compared with those in SR group, in AF group, preoperative cystatin C (Cys C), NT-proBNP,hs-cTNT and RDW levels were significantly increased, while postoperatively mechanical ventilation was longer (P<0.05).Multivariate logistic regression analysis showed that age, taking statins preoperatively, left atrium diameter, NT-proBNP, hs-cTNT and RDW were independent predictors in prediction of postoperative AF after OPCAB.Values of area under curve of NT-proBNP, hs-cTNT and RDW were 0.758％, 0.857％ and 0.648％.Conclusion Age left atrium, taking statins preoperatively, NT-proBNP, hs-cTNT and RDW were independent predictors in prediction of postoperative AF after OPCAB, and NT-proBNP, RDW and hs-cTNT have well predictive values for postoperative AF.
Keywords：Coronary artery bypassoff-pumpAtrial fibrillationHigh-sensitivity troponin TRed blood cell distribution width
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 60-64 )