Clinical Effect of Ultrasound-guided Percutaneous Microwave Ablation in Treatment of Primary Small Hepatocellular Carcinoma

XIE Xuan-gang; WANG Xiang-xiang; CHEN Gui-ping

doi:10.3969/j.issn.1002-3429.2017.08.030

Abstract：Objective To investigate clinical effect of ultrasound-guided percutaneous microwave ablation in treatment of primary small hepatocellular carcinoma.Methods A total of 80 patients with small hepatocellular carcinoma admitted during January 2011 and February 2013 were divided into observation (n=40) and control group (n=40) according to random number table method.Observation group was treated with ultrasound-guided percutaneous microwave ablation, while control group was treated with surgical resection.The operative condition, therapeutic effect, complications and prognosis were observed and compared between the two groups.Results Values of operative time, intraoperative blood loss and blood transfusion volumes were significantly lower than those in control group (P<0.05).In observation group, postoperative alanine transarninase (ALT) and aspartate aminotransferase (AST) values were significantly lower, while albumin (ALB) and total bilirubin (TB) values were significantly, and postoperative hospitalization time was significantly shorter, while postoperative complication rate was significantly lower than those in control group (P<0.05).There were no significant differences in eradication rate of lesions, recurrence rate during follow-up, disease free survival rates in postoperative 3rd, 6th, 12th, 24th and 36th months and the total survival rates in postoperative 6th, 12th, 24th and 36th months between two groups (P>0.05).Conclusion Ultrasound-guided percutaneous microwave ablation in treatment of primary small hepatocellular carcinoma can achieve similar effect of by surgical treatment.However, percutaneous microwave ablation has less damage and complication with quicker recovery of liver function.