Analysis of 7 Patients with Primary Nephrotic Syndrome Misdiagnosed as Having Diabetic Nephropathy
GAO Ying-ying
WANG Hai-sheng
Abstract：Objective To investigate misdiagnosed causes and preventive measures of primary nephrotic syndrome (PNS).Methods A total of 86 PNS patients admitted January 2012 and May 2016, among whom 7 patients were misdiagnosed as having diabetic nephropathy (DN), was retrospectively analyzed.Results The misdiagnosis rate was 8.14%.Among the 7 misdiagnosed patients, 6 patients were misdiagnosed as having DN, and 1 patient was misdiagnosed as having DN and diabetic retinopathy, and the misdiagnosed time was (5.62±1.86)d.Conditions of the 7 misdiagnosed patients were not improved after symptomatic treatments for misdiagnosed diseases.After further biochemical and renal biopsy tests, 3 patients were confirmed as having membranous glomerulonephritis, 2 as having minimal lesion of nephropathia, 1 as having mesangial proliferative glomerulonephritis and 1 as having focal glomerulosclerosis, and all patients were discharged after condition improvement by Prednisone, Tripterygium Glycosides, low molecular heparin and hypoglycemic treatments for 15-30 d.Conclusion Clinical manifestations of PNS lack specificity, and it is easy to be confused with related diseases.Patients with a short history of diabetes mellitus and without hypertensive disease or other related complications should be suspected as having PNS when the patients have edema, proteinuria and abnormally increased blood and urine sugar levels simultaneously.Relevant auxiliary examinations and renal biopsy if possible should be performed in time to confirm the diagnosis in early period.
Keywords：Nephrotic syndromeMisdiagnosisDiabetic nephropathies
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 36-39 )