Analysis of Misdiagnosed Causes and Diagnosis and Treatment Suggestions of Cholesterol Crystal Embolization
JU Shang
LIU Yu-jing
ZHANG Xiao-fu
WANG Gang
GAO Yu
CAO Xin
YAN Cheng-cheng
WANG Ning
Abstract：Objective To investigate clinical features, misdiagnosed causes and diagnosis and treatment strategy of cholesterol crystal embolization (CCE).Methods Clinical data of 3 misdiagnosed patients with CCE admitted in recent years was retrospectively analyzed.Results The 3 patients with lower limb arteriosclerosis occlusion underwent lower limb intracavity angioplasty treatment, all patients had postoperative lyons blue lesions in toe extremitates skin, and then all patients were misdiagnosed as having blue toe syndrome.Abnormally increased values of renal function level, c-reaction protein (CRP), erythrocyte sedimentation rate and eosinophils were found in 3patients, of whom 2 patients were timely confirmed the diagnosis of CCE, and were forbidden with anticoagulation and thrombolytic therapy, and the prognoses were good by follow-up;1 patient was continuously treated with anticoagulation and thrombolysis, and finally died of multiple organ failure.Conclusion If patients with atherosclerosis have increased eosinophils and inflammatory index levels, skin lesions, unexplained renal injury, gastrointestinal or neurological manifestations after vascular intervention, and CCE should be considered, and therefore histopathologic examination for many times can confirm the diagnosis.
Keywords：EmbolismcholesterolAtherosclerosisMisdiagnosisBlue toe syndrome
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 21-24 )