Thyroid-stimulating Hormone Pituitary Adenomas Easily Misdiagnosed as Primary Hyperthyroidism
YE Fan-hao
LONG Biao
LI Xian-wen
YANG Meng-xue
YANG Bo
LIAO Yu-lan
LI Feng-ping
AN Xiao-juan
LI Si-cheng
LI Ya
DAI Min
Abstract：Objective To investigate the clinical features, diagnosis and treatment of thyroid-stimulating hormone pituitary adenomas.Methods The clinical date of 2 misdiagnosed cases of thyroid-stimulating hormone pituitary adenomas were reviewed.Results Both of 2 cases had thyromegaly and (or) thyrotoxicosis in the preoperative, and thyroid hormone level in free triiodothyronine and free thyroxine increased.Thyroid-stimulating hormone(TSH) level increased in case 1 and reduced in case 2, which can be diagnosed as primary hyperthyroidism preliminarily.Later, the pituitary occupying lesions was found by imaging examination.Thyroid-stimulating hormone pituitary adenomas was confirmed by surgical pathological examination and immunohistochemical staining.After the operation, with a treatment of providing glucocorticoids to patients for supplement and thyroid hormone was maintained at a normal level during the 1 year follow-up.Conclusion thyroid-stimulating hormone pituitary adenomas is clinically rare and easy to be misdiagnosed.It can be diagnosed preliminarily after comprehensive results of clinical signs and symptoms, endocrine examination and imaging examination, however, confirming the diagnosis has to be based on pathological examination.At present, resection by surgery is the best treatment of the disease.
Keywords：Pituitary neoplasmsThyroid-stimulating hormoneMisdiagnosisHyperthyroidism
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 54-57 )