Retrospective Analysis of 2 Misdiagnosed Patients with Isolated Gastroduodenal Crohn Disease
NING Xiao-yan
WANG Wei-fu
CHEN Xiao-wu
CAI Shao-wei
LI Li-xuan
WANG Jin-tao
FU Yan-yu
XU Ming
Abstract：Objective To summarize clinical features and experiences of diagnosis and treatment of isolated gastrodu-odenal Crohn disease( CD). Methods Clinical data of 2 isolated gastroduodenal CD patients was retrospectively analyzed. Results The 2 isolated gastroduodenal CD patients were all young male,and the main symptom was gastric outlet obstruc-tion. One patient had accompanied with belly ache and haematemesis,and underwent appendicectomy at 3rd d after onset,and was confirmed gastroduodenal CD on 9 th d after surgery. Another patient had accompanied with weight loss,mild anemia and hypoalbuminemia,and treatment for peptic ulcer was noneffective,and was confirmed gastroduodenal CD in more than 2 months after onset. Gastroscopes examination for the 2 patients showed that hyperemia,edema and multiple ulcers in the stom-ach and/or duodenum mucous membrane,and cobble-like hyperplasia in duodenum mucous membrane. The histopathological examination showed granulation tissues,fissuring ulcers and small abscesses in mucosa and submucosa. Digestive tract radio-graphy and colonoscopy examination showed that there was no ileocolon lesion. Pulse glucocorticoids therapy was performed for the 2 patients after confirming isolated gastroduodenal CD. Symptoms were relieved quickly,and gastroscopy examination showed the lesions had remarkable alleviated in a short time. Conclusion Clinical manifestations of isolated gastroduodenal CD include gastric outlet obstruction,and accompanied with bleeding and malnutrition sometimes,and therefore differential diagnosis with peptic ulcer should be made.
Keywords：Crohn diseaseStomach diseasesDuodenal diseasesMisdiagnosisPeptic ulcer
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 21-24 )