Preventive Effect of Three-dimensional Conformal Radiotherapy Combined with BP Concurrent Chemotherapy on Radiation Injury in Cervical Cancer
LIU Ai-hua
HE An-bing
TONG Wen-xian
WANG Hu
TIAN Qian
PENG Xiu-lan
LI Xiao-guang
XU Hui-lin
Abstract：Objective To observe preventive effect of three-dimensional conformal radiotherapy combined with BP concurrent chemotherapy on radiation injury in middle-advanced cervical cancer. Methods A total of 62 patients with mid-dle-advanced cervical cancer between January 2013 and January 2015 were divided into observation group (n=31) and con-trol group (n=31) according to random digital table method. Observation group was given three-dimensional conformal radio-therapy combined with BP concurrent chemotherapy, while control group was given conventional radiotherapy. Therapeutic effect, radiation injury, recurrence, metastasis and survival rate were compared in two groups. Results There were signifi-cant differences in therapeutic effect and total effective rate between the two groups (P<0. 05). Compared with those in con-trol group, in observation group, radiation damage rate was significantly decreased (P<0. 05), and survival rate was signifi-cantly increased (P < 0. 05). There was no significant difference in recurrence and metastasis between the two groups (P>0. 05). Conclusion Three-dimensional conformal radiotherapy combined with BP concurrent chemotherapy can significantly improve therapeutic effect of patients with middle-advanced cervical cancer, and has preventive effect on radiation injury with good security.
Keywords：Imagingthree-dimensionalDrug therapycombinationCervix neoplasmsTreatment outcomeRadia-tion injury
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 89-91 )