Application of Serum Procalcitonin Quantitative Detection in Diagnosis of Respiratory Tract Infection
ZHANG Hui-feng
ZHENG Yun-zhou
LONG Jian-guo
CAO Fei
CHAN Yu-jiao
HOU Tian-wen
Abstract：Objective To investigate application values of serum procalcitonin ( PCT) in diagnosis of patients with re-spiratory tract infection. Methods PCT detection results of 414 patients with respiratory tract infection during June 2013 and June 2015 were analyzed combined with results of sputum culture and 9 IgM type ZgM antibodys of respiratory pathogens. Re-sults Among 414 patients with respiratory tract infection, positive PCT was found in 132 patients (31. 88%), and positive spu-tum culture was found in 225 patients (54. 35%), which included 160 only positive bacteria (11 cases of only gram-positive bacteria, 96 cases of gram-negative bacteria, and 53 cases of two or more positive bacteria) , 44 cases of only positive candida, and 21 cases of both candida and bacteria positive. Among 189 patients with negative sputum culture for pathogens, 66 patients (34. 92%) were positive, and 123 patients (65. 08%) were negative for 9 IgM type antibodys of respiratory pathogens. PCT median and positive rates in detection results by sputum culture and 9 IgM type antibodys of respiratory pathogens showed statisti-cally significant differences (P<0. 05). Values of PCT median and positive rates between negative sputum culture for pathogens and negative 9 IgM type antibodys of respiratory pathogens with gram negative bacteria group, two or more positive group, and candida combined with bacteria positive group showed statistically significant differences (P<0. 05). Values of PCT median and positive rates between negative sputum culture for pathogens and positive 9 IgM type antibodys of respiratory pathogens between positive gram negative bacteria group and two or more positive group showed statistically significant differences ( P<0. 05 ) . Mortality rate of PCT positive patients (15. 15%) was significantly higher than 3. 55% of PCT negative patients in 414 patients with respiratory tract infection (P<0. 05). Conclusion Serum PCT combined with sputum culture and 9 IgM type antibodys of respiratory pathogens detection has important reference value in diagnosis of respiratory tract infection, so serum PCT detection can be regarded as a quick excluding and diagnosis test for respiratory tract infection.
Keywords：Respiratory tract infectionProcalcitoninDiagnosis
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 78-83 )