A Study on Misdiagnosis Literature of Single Disease of Misdiagnosed Disease Database:POEMS Syndrome
XU Yi-cheng
DU Ji-chen
Abstract：POEMS syndrome is a rare disease in clinical practice. Due to its complicated clinical manifestations, multiple systems are involved and lack specific symptoms and signs, and therefore, and therefore POEMS tends to be misdiag-nosed. During 2004 and 2013, a total of 31 papers related to the misdiagnosis of POEMS syndrome had been published in Chi-nese medical journals, and all these articles had been included in the misdiagnosed disease database. Through the analysis of these databases, we found that the number of cumulative misdiagnosis cases was 140, and the time of misdiagnosis duration differed from 1 month to 6 years. 6 papers referred to the misdiagnosis rate, which accounted for 85. 9%. There were 152 ca-ses of POMES syndrome misdiagnosed as other disease. The range of POEMS misdiagnosed as other diseases had a very wide scope with a total of 36 kinds. And it mainly concentrated in chronic inflammatory demyelization polyneuropathy ( CIDP) , Gil-lian-Bare syndrome, and polyneuropathy. 129 cases described the association between the misdiagnosis and the outcome. 3. 1% of patients had grade Ⅲ consequences, 86. 82% of the patients had grade II consequences, 10. 08% of the patients had grade I consequences. Inadequate experience and lack of understanding of POEMS is the most common cause of misdiag-nosis. In order to reduce the rate of misdiagnosis, clinicians should have a comprehensive clinical thinking style as a whole and master the relevant knowledge of the disease, perform the proper laboratory examination as serum ( urine) immune-fixed electrophoresis and VEGF determination, and necessary auxiliary examination.
Keywords：POEMS syndromeMisdiagnosisPolyneuropathiesGillian-Bare syndrome
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 32-35 )