Effect on Patients with Intrafractional Errors Resulting from Volumetric Modulated Arc Therapy and Step-and-shoot IMRT Techniques in Cervical Cancer Radiotherapy
WANG En-yang
XU Fei
JIA Ming-xuan
Zeng Yue-can
Abstract：Objective To analyze the effect on patients with the intrafractional errors resulting from volumetric modu-lated arc therapy ( VMAT) and intensity modulated radiation therapy ( IMRT) techniques in cervical cancer radiotherapy. Methods Clinical data of 20 cases of cervical cancer diagnosed by pathological diagnosis in our center during October 2013 to July 2014 were analyzed according to the different methods of radiotherapy, and were divided into VMAT group and IMRT group ( n=10 each group) . All the patients with cervical cancer accepted kV-CBCT ( kilovoltage cone-beam computed tomo-graphy) scans after initial setup, correction and treatment with Elekta synergy accelerator. By acquiring kV-CBCT images and planned CT images, the errors of patients after initial setup were measured after correction and treatment on the X axis ( left-right, LR) , the Y axis ( superior-inferior, SI) and Z axis ( anterior-posterior, AP) , respectively. By the measurement of er-rors, the intrafractional errors of patients with cervical cancer in the radiotherapy were estimated and compared between the two groups. Results By using VMAT technique, the intrafractional errors of patients in the LR, SI and AP were less than that of IMRT group in three dimensional directions (P=0. 009;P=0. 008;P=0. 009). Abdominal pain occurred in 9 patients and acute radiation-induced enteritis occurred in 1 patient in the VMAT technique; abdominal pain occurred in 7 patients and acute radiation-induced enteritis occurred in 3 patient in the IMRT technique. Conclusion In cervical cancer radiotherapy, compared with IMRT technique, VMAT technique can achieve lower rate of intrafractional errors and can improve the accuracy of cervical cancer radiotherapy, which is worthy of clinical application.
Keywords：Uterine cervical neoplasmVolumetric modulated arc therapyIntensity modulated radiation therapykV-CBCT
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 89-93 )