Clinical and Pathological Misdiagnosis Analysis of 7 Cases of Axillary Metastatic Malignant Melanoma
LIU Jinga
ZHANG Ruib
CAO Penga
ZHU Zheng-longa
Abstract：Objective To investigate the clinical and pathological characteristics of axillary metastatic malignant mel-anoma, and improve correct diagnosis rate of the disease. Methods Clinical and pathological data of 7 cases of axillary ma-lignant melanoma were analysed retrospectively. Results The average age of the 7 cases was 60. 1 years old. Only two cases were diagnosed correctly, and the other five cases were misdiagnosed as lymphoma, spindle cell sarcoma, malignant peripheral nerve sheath tumor, lung carcinoma, and Malignant neurofibrosarcoma. The 7 patients underwent radical surgery, and then were diagnosed by pathology and immunohistochemistry. S-100 protein was positive in all the cases, HMB-45 was positive in 2 cases. After surgical operation, 3 patients lost follow-up, and 1 died. Conclusion There are no special and typical clinical features of axillary malignant melanomas. The tumor cells are very complex and diverse. So they may be easily misdiagnosed. Pathological and clinical physicians should be aware of the possibility of the disease in the diagnosis, and should carefully asked about the history of the case and perform physical examinations. Pathological diagnosis should be made with the help of immunohistochemistry, special staining or electron microscopy.
Keywords：MelanomaAxillaryMisdiagnosisLymphomaSarcomaPathologymolecularImmunohistochemistry
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 12-15 )